商品名：Atarax, Vistaril
Antihistamine (H1 blocker) of the piperazine class. Like other antihistamines, hydroxyzine acts by blocking the H1 receptor and suppresses inflammatory reactions caused by histamine. The H1 blockers have been used to control pruritus and skin inflammation, rhinorrhea, and airway inflammation. Hydroxyzine also has sedative properties and other calming effects on the central nervous system that are not related to the antihistamine effects. Another antihistamine, cetirizine, is an active metabolite of hydroxyzine. In dogs, most of the antihistamine effect of the administration of hydroxyzine is f
In animals it has been used to treat pruritus. Efficacy in animals for treating pruritus is low. Although it has been shown in experimental animals to suppress histamine response, it has not been consistently effective relieving pruritus in dogs with atopic dermatitis. Other uses include allergic airway disease and rhinitis. However, efficacy is not established for these uses. In people, additional uses include treatment of anxiety and psychoneurosis and as a sedative before and after general anesthesia.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
精確單方產品、鹽類等效效價、濃度、物種、route、適應症、每隻固定量或體重基準、QT／心臟／電解質、尿路／腸胃阻塞、青光眼、癲癇、器官、繁殖及併用藥門檻完成前封鎖執行；貓固定總量絕不可按體重倍增。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。