商品名:Orudis-KT (human OTC tablet), Ketofen (veterinary
Ketoprofen, like other NSAIDs, produces analgesic and anti-inflammatory effects by inhibiting the synthesis of prostaglandins. The enzyme inhibited by NSAID is the cyclo-oxygenase enzyme (COX). The COX enzyme exists in two isoforms: COX-1 and COX-2. COX-1 is primarily responsible for synthesis of prostaglandins important for maintaining a healthy GI tract, renal function, platelet function, and other normal functions. COX-2 is induced and responsible for synthesizing prostaglandins that are important mediators of pain, inflammation, and fever. However, it is known that there is some crossover
Ketoprofen is an NSAID and is used for treatment of moderate pain and inflammation. It has a half-life in most animals of less than 2 hours, but it has a duration of action for up to 24 hours. Ketoprofen is not registered in the US for small animals but has been labeled for dogs and cats in other countries. It has been 416 Ketoprofen given by injection for acute treatment and by tablet for long-term use. In dogs and cats, it has been shown effective for treating pyrexia. In horses, ketoprofen is used for musculoskeletal inflammation and pain, abdominal pain, and other inflammatory conditions.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
酮洛芬是高風險非類固醇消炎藥。只有在精確產品、物種、病患、途徑、適應症、期間、共同用藥、生殖與食物鏈條件完整時才能判讀;通用 runtime、計算與處方維持關閉。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
renal