商品名:Narcan and Trexonil
Opiate antagonist. Naloxone competes for opiate receptors and displaces opioid drugs from these receptors, thus reversing their effects. Naloxone is capable of antagonizing all opiate receptors.
Naloxone is used to reverse the effects of opiate agonists on receptors. Naloxone should be used to reverse overdoses or toxicity. It will reverse effects of morphine, oxymorphone, butorphanol, hydromorphone, and other opioids. It is less effective for reversing buprenorphine and may be titrated in gradually to achieve the optimum amount of reversal. At very low doses (one fifth of the dose needed to fully reverse opiates) it has been used to treat opioid-induced side effects such as vomiting, nausea, and dysphoria. A formulation for wildlife use (Trexonil) is more concentrated and used to rev
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
Naloxone 是急救逆轉藥;所需量與重複取決於原 opioid、製劑、曝露、route、反應及 exact naloxone product。體重-only 或跨產品輸出會延誤通氣或造成濃度錯誤。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
60-100 minutes