商品名:Pitocin, Syntocinon (nasal solution), and generic
Oxytocin stimulates uterine muscle contraction via action on specific oxytocin receptors. When administered around the time of luteolysis it stimulates PGF2-alpha secretion and disrupts luteolysis. When administered prior to luteolysis, it does not induce PGF2-alpha, and disrupts luteolysis and prolongs CL function.
Oxytocin is used to induce or maintain normal labor and delivery in pregnant animals. In surgery it may be used postoperatively following cesarean section to facilitate involution and resistance to the large inflow of blood. In large animals, oxytocin is used to augment uterine contractions and stimulate lactation. It will contract smooth muscle cells of the mammary gland for milk letdown if the udder is in a proper physiological state. It is also used to expel the placenta after delivery. However, efficacy for retained placenta is questionable, and some experts believe that estrogen should be administered in addition to oxytocin. Oxytocin does not increase milk production, but it will stimulate contraction leading to milk ejection. Oxytocin administered prior to luteolysis (prior to day 1
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
任何劑量前須確認足月、真正非阻塞性適應症、子宮頸完全擴張、產道通暢、胎位/大小/數量可順產、母體穩定與胎兒存活;並記錄產品/濃度/法域/途徑/時機/前次劑量,具備連續子宮胎心監測與即時剖腹產能力。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
renal