商品名：Noxafil
Antifungal drug. Posaconazole is a relatively new antifungal of the azole group, similar to itraconazole in structure and activity. Action against fungi is similar to other azoles, which is to inhibit ergosterol synthesis in the fungal cell membrane and produce fungistatic activity. It is active against the same fungal organisms as itraconazole, but in vitro activity is twice as great. The most important difference in activity is that posaconazole has better activity against Mucor and Zygomycetes Contraindications and Precautions Avoid use in pregnant or breeding mares until more information becomes available on safety. Drug Interactions No drug interactions have been reported. 628 Posaconazole compared to other azoles. In dogs, there is a food effect on absorption with oral systemic avail
The use of posaconazole has been limited to a few case reports and anecdotal experience. In cats it has been used to treat fungal infections refractory to other drugs such as Aspergillosis and Mucor infections. In humans it is used for invasive fungal infections, including those caused by Aspergillus and Candida. It is also active against dermatophytes, Histoplasma capsulatum, Blastomyces dermatitidis, Coccidioides immitis, and Cryptococcus neoformans. Its advantage over other azole drugs is the activity against Zygomycetes and Mucor.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
全身性懸液、延釋錠、PowderMix、IV、調劑品與犬耳道複方不可互換；須完成產品、物種、感染病原／部位、製劑、食物、TDM、肝臟與交互作用 gate，否則全面 fail closed。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。