商品名:Xarelto (Bayer/Janssen)
Rivaroxaban is a direct oral anticoagulant (DOAC) that selectively inhibits Factor Xa, a key enzyme in the coagulation cascade. By blocking Factor Xa, it interrupts both the intrinsic and extrinsic coagulation pathways, reducing thrombin generation and clot formation. Does not require antithrombin III as a cofactor (unlike heparin).
Prevention and treatment of arterial thromboembolism (ATE) in cats with cardiomyopathy. Used alone or in combination with clopidogrel for high-risk cats (ACVIM consensus guidelines).
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
現有犬用自由文字把建議每日總量寫成 q12–24h,可能造成每日總量加倍;犬自動結構值又低約 10–40 倍。貓固定 2.5 mg/貓資料只屬特定研究族群。完成血栓適應症、出血史、血小板/凝血、腎肝功能、合併抗栓藥/NSAID、產品強度、分錠或調劑與監測計畫前,封鎖通用計算與飼主劑量。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。