商品名:Alfaxan (previous name was alphaxalone)
Alfaxalone is chemically alfaxalone-2-hydroxypropyl-beta-cyclodextrin (HPCD). It is a synthetic neuroactive steroid that interacts with GABA receptors in the central nervous system to produce anesthesia and muscle relaxation. Alfaxalone is related to an older Precautionary Information Adverse Reactions and Side Effects No serious adverse effects have been identified; however, use in animals has been uncommon. In people, esophageal injury and erosion are important problems. When administering to animals, ensure that the entire medication is swallowed and followed with water. Contraindications a
Alfaxalone is used as a general anesthetic agent. It can be injected directly into the cephalic vein or delivered via constant rate infusion. If injected directly, administer over 60 seconds to allow enough time to cross the blood–brain barrier. It has been used safely with other anesthetic agents (e.g., propofol), and in combination with premedications (e.g., opiates, atropine, phenothiazines, benzodiazepines, and NSAIDs).
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
各國產品、物種、麻醉前用藥、誘導、間歇追加、CRI 與吸入維持的方案不同,且必須緩慢靜脈滴定至效果。欄位研究範圍不是一般計算上下限;在系統能表達完整麻醉方案與立即氣道/通氣支援前,不提供通用計算或飼主劑量。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)