商品名:Duragesic
Synthetic opiate analgesic. Fentanyl is approximately 80 to 100 times more potent than morphine. Fentanyl is an agonist for the mu-opiate receptors on nerves and inhibits release of neurotransmitters involved with transmission of pain stimuli (such as Substance P). The central sedative and euphoric effects are related to mu-receptor effects in the brain. The fentanyl transdermal system delivers fentanyl through the skin at a constant rate to produce systemic effects. Absorption is determined by the surface area for absorption. Patches are available that deliver 25, 50, 75, and 100 mcg/hr. Abso
Transdermal absorption and effective plasma concentrations have been demonstrated for cats, dogs, horses, and goats. Fentanyl transdermal has the same properties as fentanyl citrate administered IV, except in this formulation it is administered transdermal to produce pain relief and as an adjunct to other drugs in perioperative patients and in patients with chronic pain. In dogs, fentanyl transdermal patches (50 mcg/hr) are appropriate for most average-size dogs. Transdermal fentanyl has been shown effective to relieve postoperative pain in dogs. Transdermal fentanyl has Fentanyl, Transdermal
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
必須先確認精確動物、疼痛診斷、風險因子、所有併用藥與是否真的需要高效力鴉片類藥物。 必須核對精確製品、藥物型態、釋放設計、標示強度或濃度、完整性、法規地區與目前核准及供應狀態。 不得把人體貼片、已撤銷核准的犬用經皮溶液、注射劑、黏膜製品或調製品視為可互換。 必須由獸醫建立鎮痛、鎮靜、呼吸、循環、體溫、腸胃活動、黏著與脫落、吞食、熱暴露及救援處置計畫。 必須建立人員接觸、兒童接觸、殘藥、遺失製品、濫用與轉移風險控制;不得由通用衛教產生使用或處置方法。 任何食用動物、繁殖、幼年、老年、虛弱、呼吸疾病或肝腎功能異常情境都需獨立審核。 所有併用藥必須人工逐對核對;人體類別警告或舊自動配對不得回填獸醫交互作用結論。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
45 minutes