商品名:Xylocaine and generic brands
Local anesthetic. Lidocaine inhibits nerve conduction via sodium channel blockade. Class-1 antiarrhythmic. Decreases Phase 0 depolarization without affecting conduction. After systemic administration lidocaine is metabolized to monoethylglycinexylidide (MEGX), which also has antiarrhythmic properties. Lidocaine also has analgesic properties after systemic administration. During intravenous infusion, it may decrease pain response. In horses, infusions of lidocaine have decreased postoperative ileus either through a direct effect, via suppression of painful stimuli, or through anti-inflammatory
Lidocaine is used commonly as a local anesthetic and for acute treatment of ventricular arrhythmias. Lidocaine should be used cautiously for treating supraventricular arrhythmias because it may increase cardiac conduction. Lidocaine also is used for pain management. It has been administered as a constant rate infusion (CRI) in animals, especially in postsurgical patients. Lidocaine has been combined with other analgesics, which may be synergistic and allow lower doses of each individual component. One example of a combination is MLK, which is morphine (or fentanyl), lidocaine, and ketamine. Li
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
安全使用取決於精確產品、鹽基換算、濃度、防腐劑、epinephrine、所有局麻藥累積量、物種、途徑、適應症與監測環境。現行犬 2–8 mg/kg 會把約 30 分鐘累積上限誤呈現成可一次給藥上限,也無法區分局麻、硬膜外、喉咽噴劑、CPR、抗心律不整、CRI 與馬用途,因此封鎖通用計算與處方。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。