商品名:Zofran
Antiemetic drug from the class of drugs called serotonin antagonists. Like other drugs of this class, ondansetron acts by inhibiting serotonin type 3 (5-HT3) receptors. It is used primarily as an antiemetic during chemotherapy, for which it has been effective by blocking emetic stimuli that release serotonin. During chemotherapy, or following GI injury, there may be 5-HT released from the GI tract that stimulates vomiting centrally. This stimulus is blocked by this class of drugs. These drugs also have been used to treat vomiting from other forms of gastroenteritis, pancreatitis, and inflammat
Ondansetron, like other serotonin antagonists, is used to prevent vomiting. Although it may be effective for treating nausea and vomiting from other sources, the most common use is for preventing vomiting from chemotherapy. There is only limited efficacy information available for ondansetron effectiveness in animals. Oncologists have found it to be effective for managing vomiting from chemotherapy in animals. 558 Orbifloxacin Instructions for Use Ondansetron has been used in dogs and cats. Granisetron is a similar drug that has been substituted for a similar purpose. Patient Monitoring and Lab
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
公開犬貓資料依途徑與情境而異,犬口服暴露低且變異大;目前服務又缺適應症、阻塞、產品、ABCB1、QT、血清素與肝病閘門。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
50-60%