Granisetron, like ondansetron or dolasetron, exerts its antinausea and antiemetic actions by selectively antagonizing 5-hydroxytryptamine3 (5-HT3; serotonin3) receptors. These receptors are found primarily in the CNS chemoreceptor trigger zone, on vagal nerve terminals and enteric neurons in the GI tract. Chemotherapy associated vomiting in cats is believed primarily due to activation of 5-HT3 receptors in the chemoreceptor trigger zone (CTZ), but in dogs, enteric and vagal receptors may be more important.
In veterinary species, griseofulvin is approved for use in dogs and cats to treat dermatophytic fungal (see below) infections of the skin, hair and claws, and to treat ringworm (caused by _T. equinum_ and _M. gypseum_ ) in horses. It has also been used in laboratory animals and ruminants for the same indications. The oral tablets approved for dogs and cats are no longer marketed in the USA, but human
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
必須先由獸醫師確認嘔吐或噁心的病因、物種、共病、腸胃阻塞風險、心律與電解質風險及同步藥物。 任何考慮使用都必須重新核對精確成品、鹽與游離鹼表達、途徑、臨床情境與監測計畫。 實驗性順鉑誘發嘔吐模型不能轉成自然病例、腫瘤病患、一般胰臟炎或另一物種療程。 在完整獸醫臨床契約與主審批准前,系統不得計算、開立、輸出或建立自動交互作用。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
9-24 hours