商品名:Dibenzyline
Alpha1-adrenergic antagonist. Phenoxybenzamine binds to and antagonizes alpha1 receptor on smooth muscle causing relaxation. It is a nonselective alpha-receptor (alpha-1 and alpha-2) antagonist. It affects both alpha-1a and alpha-1b receptors. It is a potent and long-acting vasodilator.
Phenoxybenzamine is used primarily to treat peripheral vasoconstriction. In some animals, it has been used to relax urethral smooth muscle. Urethral smooth muscle is innervated by alpha-1 adrenergic receptors. This property has been used to treat urethral spasm in cats after urethral blockage. Experimentally, phenoxybenzamine has been used to relax vascular smooth muscle in horses for treating laminitis. However, this has not been a common clinical use. Phenoxybenzamine Hydrochloride 603 P Instructions for Use Results of clinical studies in animals have not been reported. Use in animals (and d
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
任何執行前必須由獸醫師核實精確鹽型與成品、司法管轄與取得狀態、物種與診斷、機械性阻塞排除、血容量與血流動力狀態、完整劑量與滴定契約、監測與反應、失敗與停止條件、救援與共同治療、食用動物殘留及競賽規則;本候選不提供可執行數值。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
20-30%
24 hours