商品名:Mithracin and Mithramycin
Anticancer agent. The action of plicamycin is to complex with DNA in the presence of divalent cations and inhibit DNA and RNA synthesis. It lowers serum calcium and may have direct action on osteoclasts to decrease serum calcium. Polyethylene Glycol Electrolyte Solution 621 P
Plicamycin is used in cancer protocols for carcinomas and treatment of hypercalcemia. Use in animals has been primarily derived from empirical use. There are no well- controlled clinical studies or efficacy trials to document clinical effectiveness.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
僅有犬嚴重高血鈣的小型歷史性院內 slow-IV 證據,且舊人用產品已退市;exact product、合法性、IV 製備、物種、病因與完整監測 gate 未齊前全面 fail closed。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。