商品名：Cardalis, Prilactone, Tempora, Aldactone*, Spironolactone*
Aldosterone receptor antagonist that acts on the kidneys as a weak potassium-sparing diuretic (preventing sodium resorption in the distal tubule) and acts on the myocardium and vasculature to inhibit aldosterone-mediated fibrosis and remodelling.
Treatment of congestive heart failure. Authorized for use in combination with standard therapy for treatment of CHF caused by valvular regurgitation in dogs. Used in the management of ascites secondary to hepatic failure (when hypokalaemia can exacerbate hepatic encephalopathy) and in treatment of hyperaldosteronism due to adrenal tumours. Spironolactone is a weak diuretic and does not have a diuretic effect in healthy dogs. Its beneficial effects in heart failure appear to be related to inhibit
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
現行資料模型無法強制區分犬貓 spiramycin-metronidazole 複方與牛用單方 spiramycin；在呼叫端強制產品／有效成分／法域／物種／途徑／感染／體重／療程／食用動物條件前不可自動計算。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。