商品名:Lamisil
Antifungal drug. Terbinafine belongs to the allylamine group of antifungal drugs. It acts on ergosterol biosynthesis by targeting fungal squalene epoxidase (SE). SE is a membrane-bound enzyme and is involved in the conversion of squalene into squalene 2,3-epoxide, which is subsequently converted into lanosterol and ergosterol. Terbinafine is selective for fungal SE. Terbinafine is active against dermatophytes. After administration, concentrations persist in hair for much longer than in plasma or other body fluids. For example, concentrations were maintained in cat hair for more than 5 weeks af
Terbinafine is indicated for treatment of dermatophyte infections in dogs, cats, birds, and some exotic animals. For dermatophytes in animals, the doses necessary for efficacy are much higher than those used in people. Although there has been experience with using terbinafine in animals—primarily for dermatophytes—there is no evidence that terbinafine is more effective than other oral antifungal agents. In dogs it has been used for Malassezia yeast infections. Treatment of infections in horses with terbinafine has not been successful probably because of poor absorption. 736 Terbutaline Sulfate
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
任何執行前必須由獸醫師核實鹽酸鹽或特比萘芬活性基準、精確品牌與學名成品、單方或複方、濃度與劑型、合法來源與品質、司法管轄及實際取得狀態、物種、年齡、體重、感染部位、病原與藥敏、疾病嚴重度、免疫狀態、完整劑量與上限、共同局部或環境處置、肝腎與血球及眼耳基線、監測、反應與失敗門檻、停止與救援、共同用藥、繁殖與泌乳狀態、食用動物殘留及競賽規則;本候選不提供可執行數值。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
40%
36 hours