最後更新:2026年10月1日
同時或先後發生兩個以上內分泌腺腫瘤的症候群。犬貓罕見。可累及甲狀腺、副甲狀腺、胰臟內分泌細胞、腎上腺與腦下垂體。
貓腫瘤的惡性比例較犬高,早期偵測影響預後
犬為小動物腫瘤最常見的物種之一,腫瘤發生率隨年齡增長而增加
這頁有幾個欄位是同系統共用的模板,還沒針對本疾病單獨改寫過。請以臨床判斷為準,記得對照下方文獻。
建議:化療前後積極利尿(cisplatin)或維持量
監測頻率:化療後 7-10d (nadir)
[1]Comparative exploration of the carotid body in domestic animals: morphology, physiology, histology, and pathology.
[2]The Thyroid Pathologist Meets Therapeutic Pharmacology.
[3]Role of miR-24 in Multiple Endocrine Neoplasia Type 1: A Potential Target for Molecular Therapy.
[4]Epigenetic regulation by the menin pathway.
[5]MEN4 and CDKN1B mutations: the latest of the MEN syndromes.
[6]Veterinary Cooperative Oncology Group-Common Terminology Criteria for Adverse Events (VCOG-CTCAE v2) following investigational therapy in dogs and cats.
穩定但需注意惡化徵兆,建議安排近期門診 (stable but monitor for deterioration, schedule near-term visit)
取決於個別腫瘤的惡性程度。良性腫瘤切除預後較佳。需終生內分泌監測。
Diagnostic Approach for Multiple Endocrine Neoplasia
Measure mass dimensions, assess fixation, evaluate regional lymph nodes
FNA of mass and regional lymph nodes for cytological assessment
CBC, chemistry, urinalysis, three-view thoracic radiographs, abdominal ultrasound
Incisional or excisional biopsy for definitive diagnosis; develop treatment plan based on staging