最後更新:2026年10月1日
成骨不全症(又稱脆骨症)為第一型膠原蛋白合成缺陷導致骨骼極度脆弱的遺傳性結締組織疾病。受影響動物反覆發生病理性骨折,骨密度顯著降低。犬貓均有報告。
犬貓均罕見。比格犬、黃金獵犬有報告。
犬貓均罕見。比格犬、黃金獵犬有報告。
這頁有幾個欄位是同系統共用的模板,還沒針對本疾病單獨改寫過。請以臨床判斷為準,記得對照下方文獻。
建議:術後維持量 LRS 或 Plasmalyte,恢復進食後可停止
類型:LRS
監測頻率:每日(術後);每次回診
[1]Animal models of osteogenesis imperfecta: applications in clinical research.
[2]Preclinical Rodent Models for Human Bone Disease, Including a Focus on Cortical Bone.
[3]Reproductive options for families at risk of Osteogenesis Imperfecta: a review.
[4]Stem Cell Therapy as a Treatment for Osteogenesis Imperfecta.
[5]Modeling Rare Bone Diseases in Animals.
穩定但需注意惡化徵兆,建議安排近期門診 (stable but monitor for deterioration, schedule near-term visit)
預後視嚴重程度而定。輕度者可在小心管理下維持生活品質。嚴重型因反覆骨折預後不良。
Diagnostic Approach for Osteogenesis Imperfecta
Gait analysis, joint palpation, range of motion assessment, muscle mass comparison
Minimum 2 orthogonal views of affected region; compare contralateral side if needed
Joint fluid analysis, CT for complex fractures, arthroscopy if indicated