商品名：DES and generic brands
Diethylstilbestrol, known as DES, is a synthetic drug with estrogen effects. It differs from steroid compounds because it does not have a steroid ring. It is used for estrogen replacement in animals. When used to treat urinary incontinence, the action of DES is believed to increase sensitivity of alpha receptors in the urinary sphincter to restore continence.
DES is most commonly used to treat estrogen-responsive incontinence in dogs. Phenylpropanolamine (PPA) has been used in dogs when DES therapy is no longer effective. Conjugated estrogens (e.g., Premarin at 20 mcg/kg twice weekly) have been used in some dogs when DES is unavailable. Estriol also has been used in some dogs to treat incontinence. DES also has been used to induce abortion in dogs. Commercial forms of DES are no longer available, but it is available through some compounding pharmacies.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
先確認是被動漏尿且完成病因與感染評估，不可把所有排尿異常視為尿道括約肌機能不全。 必須確認物種、性別、絕育狀態、子宮與乳腺狀態、妊娠可能、既有血球資料、肝臟狀態與其他荷爾蒙或骨髓毒性暴露。 必須確認精確成品、法域、實際供應、濃度、製劑、監測、反應、失敗、停藥與救援計畫。 任何飼主端內容僅可質性呈現並由獸醫師個別指示。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
9.3 hours
fecal