商品名：Interceptor, Interceptor Flavor Tabs, and SafeHeart
Antiparasitic drug. Avermectins (ivermectin-like drugs) and milbemycins (milbemycin and moxidectin) are macrocyclic lactones and share similarities, including mechanism of action. These drugs are neurotoxic to parasites by potentiating glutamate-gated chloride ion channels in parasites. Paralysis and death of the parasite is caused by increased permeability to chloride ions and hyperpolarization of nerve cells. These drugs also potentiate other chloride channels, including ones gated by GABA. Mammals ordinarily are not affected because they lack glutamate-gated chloride channels, and there is
Milbemycin is used as heartworm preventative, miticide, and microfilaricide. It is also used to control infections of hookworm, roundworms, and whipworms. It also has been used in combination with flea control drugs (See Sentinel, which contains milbemycin oxime and lufenuron.) At high doses it has been used to treat Demodex infections in dogs.
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
必須確認精確活性成分、成品、複方成分、濃度或錠規格與法域，不得把其他巨環內酯、單方、耳用製劑及不同複方互換。 必須由獸醫師確認物種、年齡、體重、生殖狀態、寄生蟲種類與階段、心絲蟲感染與微絲蟲狀態、器官功能及相關基因風險。 必須以精確產品來源閉合適應症、使用方式、前置檢查、監測、停止、急救、轉診及抗藥性處置後，才可考慮個案執行。
DRUGAPI 劑量審查引用的獸醫官方標示（各標示只適用於其產品、物種與法域，不可互換）
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。