商品名:Naprosyn, Naxen, and Aleve (naproxen sodium)
Naproxen and other NSAIDs have produced analgesic and anti-inflammatory effects by inhibiting the synthesis of prostaglandins. The enzyme inhibited by NSAIDs is the cyclo-oxygenase enzyme (COX). The COX enzyme exists in two isoforms: COX-1 and COX-2. COX-1 is primarily responsible for synthesis of prostaglandins important for maintaining a healthy GI tract, renal function, platelet function, and other normal functions. COX-2 is induced and responsible for synthesizing prostaglandins that are important mediators of pain, inflammation, and fever. However, there are overlapping functions of the m
Naproxen is approved for use in people and is popular for treating osteoarthritis. It has been used for treatment of musculoskeletal problems, such as myositis and osteoarthritis in dogs and horses. There are no veterinary formulations marketed. Its use has diminished because there are registered drugs approved for these indications for horses and dogs.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認 naproxen 本體或 sodium 鹽、原包裝、精確商品、法域、濃度、劑型、效期、重配或開封狀態與實際供應 確認物種、年齡、體重、食用動物身分、適應症、途徑、暴露或治療情境與先前 NSAID/corticosteroid 使用 評估水合、血容量、腎肝心功能、胃腸潰瘍或出血、凝血、懷孕泌乳繁殖狀態與全部合併用藥 建立血液、血清生化、尿液、GI 出血、療效、不耐受停藥與緊急轉診的人工監測契約 犬貓人用產品、美國馬用顆粒、馬用注射與研究暴露永久分流;核准不得視為供貨
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。