Nitroprusside is an immediate acting intravenous hypotensive agent that directly causes peripheral vasodilation (arterial and venous) independent of autonomic innervation. It produces a lowering of blood pressure, an increase in heart rate, a mild decrease in cardiac output, and a significant reduction in total peripheral resistance. Unlike the organic nitrates, tolerance does not develop to nitroprusside.
While nizatidine acts similarly to cimetidine and ranitidine as an H2 blocker to reduce gastric acid secretion in the stomach, in small animal medicine its use has been primarily for its prokinetic effects. It may be useful to treat delayed gastric emptying, pseudo-obstruction of the intestine and constipation. H2 blockers may be useful in preventing hemorrhagic necrosis in feline pancreatitis.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認活性離子、鈉鹽水合狀態與確切成品 確認濃度、載體、稀釋、遮光、相容性與使用期限 確認物種、診斷、疾病階段、血流動力學目標、途徑與設備 確認即時血壓、灌流、酸鹼、器官功能與氰化物相關毒性監測能力 逐對完成雙向交互作用、嚴重度與處置契約
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
renal