商品名:Veraflox
Fluroquinolone antibacterial drug. Pradofloxacin is of the new generation of fluoroquinolones. This new generation of fluoroquinolones, with substitutions at the C-8 position (e.g., C-8 methoxy), have as their advantage a broader spectrum that includes anaerobic bacteria and gram-positive cocci. The difference in spectrum of activity is largely caused by increased activity against the DNA-gyrase of gram-positive bacteria, rather than activity against topoisomerase IV, which is the target in gram-positive bacteria for the older quinolones (e.g., enrofloxacin, marbofloxacin, orbifloxacin, difloxacin). These newer fluoroquinolones (referred to by some authors as the third-generation fluoroquinolones) include gatifloxacin, gemifloxacin, and moxifloxacin. Susceptibility data indicate that it is
Pradofloxacin has been evaluated in dogs and cats, with efficacy studies published in research abstracts and clinical reports in which it has been used for treating skin and 636 Pradofloxacin soft tissue infections in dogs and cats, respiratory infections in cats, and urinary tract infections. At a dose of 3 mg/kg orally it was effective for treatment of urinary tract infections in dogs, and at 3 or 5 mg/kg it was effective for canine pyoderma. At a dose of 5 mg/kg in a 2.5% oral suspension it was effective for urinary tract infections in cats. It has been used to effectively treat infections caused by Chlamydophila felis or Mycoplasma in cats (5 mg/kg q12h, PO, for 28 days), although it was not more effective than doxycycline. It has been used to treat feline rhinitis caused by Mycoplasma
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
Pradofloxacin 劑量依產品、法域、物種、感染部位與敏感菌、年齡/生長狀態、腎功能、中樞神經病史及併用藥而異;通用計算器不得自動處方。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
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