Procarbazine’s precise mode of action is not well understood, but it is considered by most to be an alkylating agent, as it appears to inhibit protein, RNA, and DNA synthesis. Procarbazine is autooxidized into hydrogen peroxide, which may also directly damage DNA.
Prochlorperazine as a single agent is used in dogs and cats as an antiemetic. The only approved products for animals are combination products containing prochlorperazine, isopropamide, with or without neomycin ( _Darbazine_ ® _, Neo-Darbazine_ ®—SKB Labs) which are no longer marketed in the USA. The approved indications for these products include: vomiting, non-specific gastroenteritis, drug induced diarrhea, infectious diarrhea, spastic colitis, and motion sickness in dogs and cats (injectable product only).
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
公開獸醫數值未同時閉合精確產品、製劑品質、疾病亞型、完整合併療程、個體化減量、監測與專科判斷閘門；因此所有劑量計算與飼主劑量都必須封鎖。
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。
renal