商品名:Simparica (Zoetis)
Sarolaner is an isoxazoline ectoparasiticide that inhibits GABA and glutamate-gated chloride channels in arthropods. Systemically distributed after oral administration; parasites are exposed when feeding on the treated host. Causes uncontrolled neuromuscular activity leading to paralysis and death of fleas, ticks, and mites.
Treatment and prevention of flea and tick infestations in dogs. Available as Simparica (sarolaner alone) and Simparica Trio (sarolaner + moxidectin + pyrantel pamoate for heartworm, fleas, ticks, roundworms, hookworms).
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
runtime 無法聯合強制精確有效成分與商品、法域及現行法規狀態、犬用單方身分、途徑、目前精確體重、整錠分帶、商品特定年齡、寄生蟲與期間、完整吞食及補給處理、神經/生殖狀態、抗寄生蟲重複暴露、複方隔離,以及可能變動的 NWS EUA、傷口照護、通報與紀錄條件。三十九張數值證據卡全部只能供查閱。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。