Tolfenamic acid exhibits pharmacologic actions similar to those of aspirin. It is a potent inhibitor of cyclooxygenase, thereby inhibiting the release of prostaglandins. It also has direct inhibition of prostaglandin receptors. Tolfenamic acid has significant anti-thromboxane activity and is not recommended for use pre-surgically because of its effects on platelet function.
Toltrazuril is an antiprotozoal agent that may be considered as an alternative treatment for coccidiosis in dogs and cats, Hepatazoon infections, or for treating the oocyst shedding stage of toxoplasmosis in cats. It has also been used as a treatment for overwhelming parasitic loads in lizards (Bearded Dragons). Toltrazuril has activity against parasites of the genus _Hepatozoon_, but other drugs ( _e.g.,_ imidocarb, primaquine, doxycycline) are generally used. While toltrazuril has been used to treat equine protozoal myeloencephalitis (EPM) caused by _Sarcocystis neurona_, use of approved products now available ( _e.g.,_ nitazoxanide, ponazuril, pyrimethamine/sulfadiazine) is preferred. Toltrazuril has been used in some countries to treat _Isospora_ _suis_ in piglets.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
API 無法同時強制精確產品/濃度/錠型、現行法域、物種/體重、途徑、適應症、食用身分/停藥期、生殖狀態、交互作用與監測,因此 52 張數值卡均不可執行。異藥微克級逆轉療程已由 overlay 清空。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。