最後更新：2026年10月1日
麻醉誘發的遺傳性肌肉代謝異常,導致快速高體溫、肌肉僵硬及代謝性酸中毒。需緊急處理。
Feline emergencies frequently include urethral obstruction (FIC/FLUTD in male cats), ATE, dyspnea (CHF, asthma, pleural effusion), and trauma (high-rise syndrome). Cats are adept at masking pain — subtle changes in behavior may indicate severe distress.
某些品種易感(如鬥牛犬)
這頁有幾個欄位是同系統共用的模板，還沒針對本疾病單獨改寫過。請以臨床判斷為準，記得對照下方文獻。
立即停止所有觸發藥物（吸入麻醉劑、succinylcholine），給予 dantrolene 1-3 mg/kg IV，積極降溫（冰敷、冷 IV fluids），矯正酸血症及電解質異常。
建議：Shock dose crystalloid 20-30 mL/kg IV bolus（犬），10-15 mL/kg（貓），評估反應後調整
速率：20-30 mL/kg
監測頻率：q2-4h
[1]Expanding diverse horizons in smooth muscle research: a symposium review of "Muscle and Pathology/Health: Frontiers of Translational Research" at the 66th Annual Meeting of Japan Society of Smooth Muscle Research.
[2]Preclinical model systems of ryanodine receptor 1-related myopathies and malignant hyperthermia: a comprehensive scoping review of works published 1990-2019.
[3]Conserving wildlife in a changing world: Understanding capture myopathy-a malignant outcome of stress during capture and translocation.
[4]Putative malignant hyperthermia mutation CaV1.1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance.
[5]Isoflurane Alters Presynaptic Endoplasmic Reticulum Calcium Dynamics in Wild-Type and Malignant Hyperthermia-Susceptible Rodent Hippocampal Neurons.
屬於急診緊急處置，延遲治療顯著增加死亡率 (delay significantly increases mortality)
飼主衛教
用藥指引
⚠ 警訊症狀（立即回診）
環境調整
長期計畫：依根本病因制定長期計畫
限制活動
穩定後漸進恢復活動
期間：依病因
無Dantrolene死亡率>70%。有Dantrolene存活率改善。
惡性高體溫 診斷流程
詳細問診包括發病經過、用藥史、飲食與環境
CBC、生化全套、尿液分析
來源：自動產生