商品名:Panacur and SafeGuard
Benzimidazole antiparasitic drug. Like other benzimidazoles, fenbendazole produces a degeneration of the parasite microtubule and irreversibly blocks glucose uptake in parasites. Inhibition of glucose uptake causes depletion of energy stores in parasite, eventually resulting in death. However, there is no effect on glucose metabolism in mammals.
Fenbendazole is effective for treatment of numerous helminth intestinal parasites in animals, including Toxacara, Toxascaris, Ancylostoma, and Trichuris. In dogs it is 304 Fenbendazole effective for most intestinal helminth parasites and also against nematodes. Fenbendazole has been effective for treatment of Giardia, but higher doses are needed and there may be failure rates as high as 50%. It is effective in cats for treatment of lungworms, flukes, and a variety of helminth parasites.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
必須先確認動物物種、食用狀態、精確寄生蟲診斷與是否真的需要治療。 必須核對精確製品、濃度、劑型、批次標籤、法規地區與保存狀況,不得由品牌或有效成分名稱推定可互換。 必須逐項審核劑量、間隔、期間與適應症,尤其不可採用目前互相衝突的犬用 core 欄位。 犬隻若採長於標示期間的用法,必須由獸醫依基線與風險制定血液評估、追蹤與停藥門檻。 鳥類不得使用通用 bird 劑量;精確物種與製品證據缺一即阻擋。 食用動物的屠宰與乳品棄置條件必須取自當地現行精確產品標籤。 所有同時使用的驅蟲藥、驅吸蟲藥及其他藥物都必須人工逐對核對,系統不得回報無已知交互作用。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。