商品名:CoSopt*, Dorzolamide*, Dorzolamide with Timolol*, Trusopt*
Reduces intraocular pressure by reducing the rate of aqueous humour production by inhibiting the formation of bicarbonate ions within the ciliary body epithelium.
In the control of all types of glaucoma in dogs and cats, either alone or in combination with other topicals. Dorzolamide/timolol combination may be more effective in dogs than either drug alone. It may be less tolerated than brinzolamide because of its less physiological pH of 5.6. The concurrent use of a topical and a systemic carbonic anhydrase inhibitor is not beneficial as there is no additional decrease in intraocular pressure compared with either route alone.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
多佐胺單方、人用多佐胺/噻嗎洛爾複方、布林佐胺與口服乙醯唑胺/甲醯唑胺不可互換;人用標示、犬貓疾病研究、正常動物試驗、先天性青光眼族群與白內障手術情境也不可通用。未確認確切商品、單方或複方、物種、患眼、青光眼機轉與緊急程度、角膜內皮、腎肝狀態、貓血鉀與酸鹼風險、併用眼藥及噻嗎洛爾心肺門檻前,所有臨床執行均封鎖。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。