商品名:Mucomyst and Acetadote. Also referred to as
Acetylcysteine decreases viscosity of secretions and is used as a mucolytic agent in eyes and in bronchial nebulizing solutions. Acetylcysteine is a sulfhydryl compound and acts to increase synthesis of glutathione in the liver. Glutathione subsequently acts as an antioxidant and facilitates conjugation to toxic metabolites, particularly the toxic metabolites of acetaminophen. The antioxidant effects also have been used to treat conditions associated with oxidative stress.
As a donator of the sulfhydryl group, it is used as an antidote for intoxications (e.g., acetaminophen toxicosis in cats). When treating poisoning, it is important that acetylcysteine be administered as soon as possible for optimum effectiveness. Acetylcysteine also has been used to prevent contrast medium-induced nephropathy. Acetylcysteine has been used as a treatment of oxidative stress because it is a scavenger of hydroxyl radicals and hypochlorous acid. Acetylcysteine will reduce cerebral edema.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
啟用前須由主控確認確切商品或調製配方、濃度、賦形劑、途徑、物種、診斷或中毒暴露、暴露時間、呼吸道與眼表狀態、肝腎與水分狀態、繁殖狀態、共用藥、法域、處方權限及可即時監測與救援能力。
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。
50 hours