商品名:Rocaltrol and Calcijex
Vitamin D analogue, also called 1,25-dihydroxycholecalciferol. Calcitriol is normally formed in the kidneys from 25-hydroxycholecalciferol. Action of calcitriol is to increase calcium absorption from the intestine and facilitate a parathyroid hormone (PTH) effect on bone. Low calcitriol levels in animals lead to decreased intestinal calcium absorption. Animals with chronic renal failure and hyperparathyroidism often have low calcitriol levels. Calcitriol can also inhibit synthesis and storage of PTH.
Calcitriol is used to treat calcium deficiency and diseases such as hypocalcemia associated with hyperparathyroidism. It is also used to increase calcium in cats that have had parathyroid glands removed. In this use, it is often administered with calcium supplements to the diet. It is used in dogs and cats to manage calcium and phosphorous balance with chronic kidney disease. Although used by veterinarians to reduce renal secondary PTH concentrations in animals with chronic renal disease, this benefit is more controversial and not supported by strong evidence. Calcitriol should not be used as a vitamin D supplement.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
先確認藥物確為 calcitriol,並排除其他維生素 D 化合物及 calcitonin。 核對動物種別、診斷、病程階段、實際產品、劑型、濃度、載體、製造者、管轄區與調製狀態。 由獸醫依游離鈣、總鈣、磷、腎功能、相關荷爾蒙、飲食及所有鈣與維生素補充品制定個別監測與處方。 任何數值、給藥路徑、頻率、療程或交互作用結論都必須由臨床人員重建,不得由舊資料或 caller 輸入補齊。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。