商品名：Imuran and generic
Thiopurine immunosuppressive drug. Acts to inhibit T-cell lymphocyte function. This drug is metabolized to 6-mercaptopurine (6-MP), which may account for immunosuppressive effects because 6-MP interferes with purine metabolism in lymphocytes. Other cells can use salvage pathways for purine synthesis, but stimulated lymphocytes are not capable of this synthesis.
Azathioprine is used to treat various immune-mediated diseases in animals, including immune-mediated hemolytic anemia, pemphigus, and inflammatory bowel disease. It is often administered with prednisone or prednisolone. Onset of action may be delayed for 4-6 weeks in some patients. 64 Azathioprine Instructions for Use Azathioprine is usually used in combination with other immunosuppressive drugs (e.g., corticosteroids) to treat immune-mediated disease. Cats are very sensitive to the bone marrow–suppressing effects of azathioprine. Doses of 2.2 mg/kg to cats have produced toxicity, but most exp
劑量數字暫停提供：VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容，DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源；計算機可手動輸入劑量換算。
確認硫唑嘌呤本體、精確商品或調劑品、含量、劑型、批次與法域 確認物種、診斷、病期、治療目標、既往反應及所有合併藥物 建立血球與血小板、肝臟、感染、腸胃與胰臟風險的基線及持續監測計畫 個別評估貓與馬的代謝風險、犬的品種或個體差異，以及 TPMT 證據的可用範圍；TPMT 不得取代持續血球監測 逐一核對黃嘌呤氧化酶抑制劑、骨髓抑制藥、免疫抑制藥、疫苗及其他候選交互作用 確認懷孕、哺乳、繁殖、危害藥物處理、廢棄及食物鏈限制
依出現頻率分組；嚴重副作用獨立列出，臨床上需立即辨識。