商品名:Cerenia
Maropitant is an antiemetic from the same group as the human drug aprepitant (Emend). These drugs act as an antiemetic by blocking the neurokinin-1 (NK1) receptor (also known as Substance P). It has less affinity for other neurokinin receptors (NK2 and NK3). Although NK1 receptors are involved in other physiologic and behavioral responses, at doses used to control vomiting there were no adverse effects associated with blockade of other receptors. Neurokinin-1 is a neurotransmitter to simulate vomiting from the emetic center. Maropitant can inhibit vomiting that is stimulated from both central
Maropitant is approved for use as an antiemetic in dogs to inhibit vomiting from both central and peripheral sources. It has been effective to inhibit vomiting from chemotherapy, gastrointestinal disease, toxins, renal disease, vestibular stimuli (motion sickness), and circulating stimuli via the chemoreceptor trigger zone. After SQ injection it has a rapid onset and a duration of 24 hours. Although not approved for cats, it has been used safely and effectively in cats to treat vomiting from a variety of sources, such as motion sickness and stimulation by emetogenic agents, with a duration of
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
確認原包裝精確商品、濃度、劑型、鹽型與 active moiety 標示 確認物種、年齡、體重、適應症、嘔吐病因、途徑與法域 確認胃腸阻塞或毒物攝入、肝功能、心臟病、繁殖狀態與合併用藥 依精確產品標示建立監測、保存、開封後期限、穿刺上限與處置方式 標示外使用須建立有效獸醫師-飼主-動物關係並產生病患專屬處方
DRUGAPI 劑量審查引用的獸醫官方標示(各標示只適用於其產品、物種與法域,不可互換)
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。