商品名:Deltasone, Meticorten, and generic brands
Glucocorticoid anti-inflammatory drug. The effect of prednisone is attributed to prednisolone. After administration, prednisone is converted to prednisolone. Anti-inflammatory effects are complex, but via binding to cellular glucocorticoid receptors, prednisolone acts to inhibit inflammatory cells and suppresses expression of inflammatory mediators. Prednisolone is approximately four times more potent than cortisol but only one seventh as potent as dexamethasone. Prednisone appears to be well absorbed and converted to active drug in dogs. However, in horses and cats, administration of predniso
Prednisone, like other corticosteroids, is used to treat a variety of inflammatory and immune-mediated diseases. In cats, prednisone may produce therapeutic failures, and prednisolone (active drug) is preferred. There are several large animal doses cited (similar to prednisolone); however, because of poor activity in horses, the use is discouraged.
劑量數字暫停提供:VetPro 的劑量改依 DRUGAPI 藥物資料庫對外的內容,DRUGAPI 目前不提供可直接計算的劑量。下方列出 DRUGAPI 的審查結論與劑量審查引用的來源;計算機可手動輸入劑量換算。
潑尼松需先確認物種、適應症、日總量與每次量、途徑、產品、共病、療程、taper 與併用藥。貓計算器硬性封鎖並導向 D0556,但不得推算補償倍數;犬未有疾病專屬 protocol 前也不計算。
依出現頻率分組;嚴重副作用獨立列出,臨床上需立即辨識。